Blar i ODA Open Digital Archive på forfatter "Hoff, Bård Helge"
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Activity of 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines to Tetrahymena
Kaspersen, Svein Jacob; Sundby, Eirik; Charnock, Colin; Hoff, Bård Helge (Bioorganic chemistry;, Journal article; Peer reviewed, 2012-06-05)A series 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines (43 compounds), some of which are epidermal growth 22 factor tyrosine kinase inhibitors, were tested for their protozoal toxicity using an environmental Tetrahy- 23 mena ... -
Chiral N-benzyl-N-methyl-1-(naphthalen-1-yl)ethanamines and their in vitro antifungal activity against Cryptococcus neoformans, Trichophyton mentagrophytes and Trichophyton rubrum
Tvedt, Thor Håkon Krane; Kaasa, Kristin; Sundby, Erik; Charnock, Colin; Hoff, Bård Helge (European Journal of Medicinal Chemistry;68, Journal article; Peer reviewed, 2013-10)In the search for new antifungal compounds and to explore structure activity relationships, a series of 24 chiral benzyl amine type antifungals was synthesised and characterised. In vitro testing against the human pathogen ...